• Angiotensin-converting enzyme (ACE) inhibitors decrease the production of angiotensin II, reduce sympathetic nervous system activity, and increase bradykinin levels.
• ACE inhibitors are effective antihypertensive agents and slow the progression of target organ damage including various nephropathies and left ventricular hypertrophy and heart failure.
• They are also useful in reducing the mortality post-myocardial infarction and in high-risk coronary or peripheral vascular disease patients.
• The main side effects of ACE inhibitors include cough, angioedema, hyperkalaemia, and worsening of renal functions especially in the presence of renal artery stenosis.
An essential tool for everyday use in the management of hypertension, this online reference covers the different phases of investigation and definitive management, and aids clinical decision-making by collating all the relevant information and guidance in one easily accessible place.
Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up to date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or for the misuse or misapplication of material in this work.
